Which serology marker indicates immunity after Hep B vaccination?

Which serology marker indicates immunity after Hep B vaccination?

• A. +HbsAB
• B. +HbsAG
• C. +HBeAG
• D. +HbcAB

Answer: (A)

Immunity from hepatitis B vaccination is shown by the presence of antibodies to the hepatitis B surface antigen (anti-HBs). This antibody is what the vaccine drives your body to produce and provides protective immunity. A protective level is typically considered to be 10 mIU/mL or higher. The other markers indicate different things: HBsAg (surface antigen) signals an active infection; HBeAg indicates active viral replication; anti-HBc (core antibody) points to past or ongoing infection with the virus, not vaccination-induced immunity. So, a positive anti-HBs specifically reflects immunity from vaccination, whereas the others do not.

Immunity from hepatitis B vaccination is shown by the presence of antibodies to the hepatitis B surface antigen (anti-HBs). This antibody is what the vaccine drives your body to produce and provides protective immunity. A protective level is typically considered to be 10 mIU/mL or higher. The other markers indicate different things: HBsAg (surface antigen) signals an active infection; HBeAg indicates active viral replication; anti-HBc (core antibody) points to past or ongoing infection with the virus, not vaccination-induced immunity. So, a positive anti-HBs specifically reflects immunity from vaccination, whereas the others do not.